Investigating the concept of chemical functionalization in forensic applications among pharmacy students: A questionnaire study

Authors

  • Khalid W. Zainulabdeen Department of Chemistry, College of Science, Al-Nahrain University, Baghdad
  • Alaa A. Rashad Department of Chemistry, College of Science, Al-Nahrain University, Baghdad
  • Shams A. Ismeal Department of Medical Physics, College of Science, Al-Nahrain University, Baghdad
  • Muna Bufaroosha Department of Chemistry, College of Science, United Arab Emirates University, Al-Ain
  • Shaimaa A. Hussein College of Medicine, Al-Nahrain University, Baghdad
  • Omar Al-Tameemi Department of Mathematics and Computer Application, College of Science, Al-Nahrain University, Baghdad
  • Ziad Fidil College of Pharmacy, University of Thi-Qar, Nasiriyah
  • Wedad H. Al-Dahhan Department of Chemistry, College of Science, Al-Nahrain University, Baghdad
  • Rahimi M. Yusop School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor
  • Emad Yousif Department of Chemistry, College of Science, Al-Nahrain University, Baghdad https://orcid.org/0000-0003-1458-4724

Abstract

Forensic science plays a crucial role in the criminal justice system by providing essential evidence and aiding the resolution of crimes. One significant aspect of forensic science is functionalizing pharmacology, which involves the analysis of drugs and their metabolites in biological samples to ascertain their origins and potential effects. It is imperative for future healthcare professionals, particularly pharmacy students, to gain a comprehensive understanding of the functionalization of pharmacology in forensic science. However, there is a paucity of research on pharmacy students' current knowledge and comprehension in this specific domain. Hence, the present study aimed to utilize a questionnaire-based approach to explore pharmacy students' understanding of functionalizing pharmacology in forensic science. The primary objective of this investigation was to identify strengths and weaknesses within this cohort's knowledge base, ultimately offering recommendations for enhancing pharmacy education in this field.

References

Abbate, V., Schwenk, M., Presley, B. C., & Uchiyama, N. (2018). The ongoing challenge of novel psychoactive drugs of abuse. Part I. Synthetic cannabinoids (IUPAC Technical Report). Pure and Applied Chemistry, 90(8), 1255-1282.

Aljamali, N. M., & Alsabri, I. K. (2020). Development of Trimethoprim Drug and Innovation of Sulfazane-Trimethoprim Derivatives as Anticancer Agents. Biomedical and Pharmacology Journal, 13(2), 613-625.

Alomi, Y. A., Najim, R. S., Aqeeli, M. M. (2021). Pharmacist's Knowledge of Forensic Pharmacy Services. International Journal of Pharmacology and Clinical Sciences, 10, 92–101. https://doi.org/10.5530/ijpcs.2021.10.14

Alshammari, T. M., Alhindi, S. A., Alenzi, K. A., Alshammari, A. H., & Alshammari, M. A. (2019). Knowledge of antibiotic usage and awareness of antimicrobial resistance among pharmacy students and faculty members in Kuwait. Journal of Infection and Public Health, 12(6), 819-823.

Ansari, A. A., Aldajani, K. M., AlHazaa, A. N., & Albrithen, H. A. (2022). Recent progress of fluorescent materials for fingermarks detection in forensic science and anti-counterfeiting. Coordination Chemistry Reviews, 462, 214523.

Buchan, E., Hardy, M., Gomes, P. D., Kelleher, L., Chu, H. O., & Oppenheimer, P. G. (2022). Emerging Raman spectroscopy and saliva-based diagnostics: from challenges to applications. Applied Spectroscopy Reviews, 1-38.

Caldwell, J. (1996). The importance of drug metabolism studies for efficient drug discovery and development. Drug Metabolism and Pharmacokinetics, 11(1), 119-126.

Castillo-Peinado, L. S., & De Castro, M. L. (2017). An overview on forensic analysis devoted to analytical chemists. Talanta, 167, 181-192.

Chaudhary, R. G., Mahmood, S., & Jotania, R. B. (2023). Green Nanomaterials for Clean and Sustainable Environment. Current Nanoscience, 19(6), 746-747.

Dragan, A. M., Parrilla, M., Feier, B., Oprean, R., Cristea, C., & De Wael, K. (2021). Analytical techniques for the detection of amphetamine-type substances in different matrices: A comprehensive review. TrAC Trends in Analytical Chemistry, 145, 116447.

Gee, A., & Xu, X. (2018). Surface functionalisation of upconversion nanoparticles with different moieties for biomedical applications. Surfaces, 1(1), 96-122.

Iavicoli, I., Leso, V., Beezhold, D. H., & Shvedova, A. A. (2017). Nanotechnology in agriculture: Opportunities, toxicological implications, and occupational risks. Toxicology and Applied Pharmacology, 329, 96-111.

Jiang, H. L., Li, N., Cui, L., Wang, X., & Zhao, R. S. (2019). Recent application of magnetic solid phase extraction for food safety analysis. TrAC Trends in Analytical Chemistry, 120, 115632.

Kumar, R. R., Kumar, A., Chuang, C. H., & Shaikh, M. O. (2023). Recent advances and emerging trends in cancer biomarker detection technologies. Industrial & Engineering Chemistry Research, 62(14), 5691-5713.

Malve, H. O. (2016). Forensic pharmacology: An important and evolving subspecialty needs recognition in India. Journal of Pharmacy & Bioallied Sciences, 8(2), 92.

Manousi, N., & Samanidou, V. (2021). Green sample preparation of alternative biosamples in forensic toxicology. Sustainable Chemistry and Pharmacy, 20, 100388.

Mayr, A., & Machin, D. (2011). The language of crime and deviance: An introduction to critical linguistic analysis in media and popular culture. Bloomsbury Publishing.

Muehlethaler, C., Leona, M., & Lombardi, J. R. (2016). Review of surface enhanced Raman scattering applications in forensic science. Analytical Chemistry, 88(1), 152-169.

Nadar, S. S., Kelkar, R. K., Pise, P. V., Patil, N. P., Patil, S. P., Chaubal-Durve, N. S., ... & Patil, P. D. (2021). The untapped potential of magnetic nanoparticles for forensic investigations: A comprehensive review. Talanta, 230, 122297.

Peters, F. T., & Steuer, A. E. (2019). Antemortem and postmortem influences on drug concentrations and metabolite patterns in postmortem specimens. Wiley Interdisciplinary Reviews: Forensic Science, 1(1), e1297.

Petoft, A., & Abbasi, M. (2019). A historical overview of law and neuroscience: From the emergence of medico-legal discourses to developed neurolaw. Journal on European History of Law, 10(2).

Rathinavel, S., Priyadharshini, K., & Panda, D. (2021). A review on carbon nanotube: An overview of synthesis, properties, functionalization, characterization, and the application. Materials Science and Engineering: B, 268, 115095.

Roszkowska, A., Miękus, N., & Bączek, T. (2019). Application of solid"phase microextraction in current biomedical research. Journal of Separation Science, 42(1), 285-302.

Roux, C., Crispino, F., & Ribaux, O. (2012). From forensics to forensic science. Current Issues in Criminal Justice, 24(1), 7-24.

Sijen, T., & Harbison, S. (2021). On the identification of body fluids and tissues: A crucial link in the investigation and solution of crime. Genes, 12(11), 1728.

Thieme, D., Sachs, H., & Uhl, M. (2014). Proof of cannabis administration by sensitive detection of 11"nor"Delta (9)"tetrahydrocannabinol"9"carboxylic acid in hair using selective methylation and application of liquid chromatography"tandem and multistage mass spectrometry. Drug Testing and Analysis, 6(1-2), 112-118.

Vivero"Escoto, J. L., Slowing, I. I., Trewyn, B. G., & Lin, V. S. (2010). Mesoporous silica nanoparticles for intracellular controlled drug delivery. Small, 6(18), 1952-1967.

Welch, C. J. (2019). High throughput analysis enables high throughput experimentation in pharmaceutical process research. Reaction Chemistry & Engineering, 4(11), 1895-1911.

Yao, J., Yang, M., & Duan, Y. (2014). Chemistry, biology, and medicine of fluorescent nanomaterials and related systems: new insights into biosensing, bioimaging, genomics, diagnostics, and therapy. Chemical Reviews, 114(12), 6130-6178.

Yaseen, T., Pu, H., & Sun, D. W. (2018). Functionalization techniques for improving SERS substrates and their applications in food safety evaluation: A review of recent research trends. Trends in Food Science & Technology, 72, 162-174.

Zhang, X. W., Li, Q. H., & Dou, J. J. (2020). Mass spectrometry-based metabolomics in health and medical science: A systematic review. RSC Advances, 10(6), 3092-3104.

Zhou, W., Wang, Y., Lu, A., & Zhang, G. (2016). Systems pharmacology in small molecular drug discovery. International Journal of Molecular Sciences, 17(2), 246.

Zrazhevskiy, P., Sena, M., & Gao, X. (2010). Designing multifunctional quantum dots for bioimaging, detection, and drug delivery. Chemical Society Reviews, 39(11), 4326-4354.

Additional Files

Published

2025-10-04

How to Cite

Zainulabdeen, K. W., Rashad, A. A., Ismeal, S. A., Bufaroosha, M., Hussein, S. A., Al-Tameemi, O., … Yousif, E. (2025). Investigating the concept of chemical functionalization in forensic applications among pharmacy students: A questionnaire study. Indonesian Journal of Chemical Education, 2(1), 26–33. Retrieved from https://jurnal.uny.ac.id/index.php/ijce/article/view/83145

Issue

Vol. 2 No. 1 (2025): JULY 2025

Section

Articles

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